Drug class: third generation cephalosporins, sores, ulcers, or white spots on the lips or in the mouth, Abdominal or stomach cramps or tenderness, diarrhea, watery and severe, which may also be bloody, fast, irregular, pounding, or racing heartbeat or pulse, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, redness of the face, neck, arms, and occasionally, upper chest, Blistering, peeling, or loosening of the skin, red skin lesions, often with a purple center, excess air or gas in the stomach or intestines, redness, swelling, or soreness of the tongue. We comply with the HONcode standard for trustworthy health information -, Clostridium difficile-associated diarrhea. Infection 24 (1996): 98-102, 14. Ceftriaxone will not cause symptoms in everyone but is more likely to do so at higher doses. Learn from their experiences about effectiveness, side effects and cost Ceftriaxone/Dextrose Side Effects Swelling, redness, or pain at the injection site may occur. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. Check with your doctor or nurse immediately if any of the following side effects occur while taking ceftriaxone: Some side effects of ceftriaxone may occur that usually do not need medical attention. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Chemotherapy 27 (1981): 62-9, 21. Ann Pharmacother 34 (2000): 1076-7, 38. "Population pharmacokinetics of ceftriaxone and pharmacodynamic considerations in haemodialysed patients." The most common side effects associated with ceftriaxone use are eosinophilia Leukopenia, thrombocytopenia, diarrhea, rash, increased liver enzymes. Roche Laboratories, Nutley, NJ. T cell involvement was proposed as the mechanism. O 0. Renal precipitation has also been reported during postmarketing experience. These are not all of the side effects that may occur. In others, the negative effects turn out to be but were not identified until after the drug was extensively used. [Ref], Common (1% to 10%): Increased hepatic enzymes, increased ALT, increased AST, Uncommon (0.1% to 1%): Increased bilirubin, Rare (less than 0.1%): Hepatitis, jaundice, gallbladder sludge, biliary lithiasis, cholestatic jaundice, Frequency not reported: Transient elevations in liver function tests, shadows on sonograms of the gallbladder, cholelithiasis, pseudocholelithiasis, false-positive hepatobiliary scan, Postmarketing reports: Gallbladder precipitation, -Frequency not reported: Hepatic dysfunction, cholestasis[Ref], The onset of pseudomembranous colitis symptoms has been reported during or after antimicrobial treatment. Am Fam Physician 64 (2001): 737. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Severe and sometimes fatal reactions have been reported in term and premature newborns (younger than 28 days) treated with IV ceftriaxone and calcium-containing IV solutions; a crystalline material (ceftriaxone-calcium precipitate) has been observed in the lungs and kidneys at autopsy. Thiella G, Bucci L, Agrati AM, Palmieri G "Nonfatal anaphylactic shock following an unusual sensitization." N Engl J Med 354 (2006): 2794-801, 29. You may report side effects to FDA at 1-800-FDA-1088. What is the most important information I should know about ceftriaxone? Serious side effects have been reported with ceftriaxone. Ceftriaxone was significantly better than amoxicillin in the treatment. Maranan MC, Gerber SI, Miller GG "Gallstone pancreatitis caused by ceftriaxone." See the “Drug Precautions” section. Pregnancy - is it safe to take ceftriaxone during pregnancy? You may report side effects to FDA at 1-800-FDA-1088. Swelling, redness, or pain at the injection site may occur. Meyboom RH, Kuiper H, Jansen A "Ceftriaxone and reversible cholelithiasis." Ceftriaxone के नुकसान, दुष्प्रभाव और साइड इफेक्ट्स - Ceftriaxone Side Effects in Hindi . © 2005 - 2019 WebMD LLC. Allergy and cross-sensitivity For all CEPHALOSPORINS. amoxicillin, diclofenac ophthalmic, doxycycline, triamcinolone, metronidazole, azithromycin, ranitidine, cephalexin, ciprofloxacin, Keflex. This medicine may cause serious skin reactions. "Ertapenem pharmacokinetics and impact on intestinal microflora, in comparison to those of ceftriaxone, after multiple dosing in male and female volunteers." Duncan CJ, Evans TJ, Seaton RA "Ceftriaxone-related agranulocytosis during outpatient parenteral antibiotic therapy." Diarrhea 4. Ramakrishnan K, Scheid DC "Diagnosis and management of acute pyelonephritis in adults." Edema has also been reported during postmarketing experience. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Both pseudocholelithiasis (biliary "sludging") and true cholelithiasis (ceftriaxone-containing gallstone) have been reported in association with doses greater than 2 g/day. Toll LL, Lee M, Sharifi R "Cefoxitin-induced interstitial nephritis." Risk of forming precipitates was increased by duration of therapy exceeding 14 days, renal failure, dehydration, or total parenteral nutrition. Ceftriaxone is used to treat a variety of conditions such as urinary tract infections, infection of the ears, lungs and meningitis caused by bacteria. Nineteen cases (10 adults, 9 children) of immune hemolytic anemia have been reported, 9 of which were fatal. Early Lyme disease." Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, Increase In The Number Of Platelets In The Blood, A Fibrous Thickening Of The Skin Called Induration, A Decrease In The Blood Clotting Protein Prothrombin, A Decreased Number Of Lymphocytes In The Blood, A Fever As A Result Of Taking The Medication, A Significant Type Of Allergic Reaction Called Anaphylaxis, A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome, A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis, A Stone In The Common Bile Duct Called Choledocholithiasis, A Type Of Allergic Reaction Called Angioedema, A Type Of Significant Allergic Skin Reaction Called DRESS Syndrome, A Type Of Skin Disorder Called Acute Generalized Exanthematous Pustulosis, A Yellowing Of The Eyes Or Skin From Buildup Of Bilirubin Called Jaundice, Destruction Of Red Blood Cells By Body's Own Antibodies, Diarrhea From An Infection With Clostridium Difficile Bacteria, Erythema Multiforme, A Type Of Allergic Skin Reaction, Increased Risk Of Bleeding Due To Clotting Disorder, Inflammation In The Lungs Due To An Allergic Reaction, Inflammation Of The Liver Called Hepatitis, Low Levels Of A Type Of White Blood Cell Called Neutrophils, Very Low Levels Of Granulocytes, A Type Of White Blood Cell, A Condition Where There Is Excess Sugar In The Urine, A Yeast Infection Of The Vagina And Vulva, Inflammation Of The Skin Due To An Allergy, Inflammation Of The Vein, Or Phlebitis After Infusion, Stomatitis, A Condition With Painful Swelling And Sores Inside The Mouth. [Ref], Uncommon (0.1% to 1%): Increased alkaline phosphatase, Postmarketing reports: Galactosemia test false positive, false-positive test for urinary glucose (nonenzymatic methods), -Frequency not reported: Increased LDH, false-positive test for urinary glucose[Ref], Rare (less than 0.1%): Anaphylaxis/anaphylactic-type reactions (e.g., bronchospasms), serum sickness, Frequency not reported: Allergic reaction, cross-sensitivity, Postmarketing reports: Anaphylaxis (anaphylactic shock, transient leukopenia, neutropenia, agranulocytosis, thrombocytopenia), anaphylactic reaction, anaphylactoid reaction, hypersensitivity, -Frequency not reported: Allergic reactions, serum sickness-like reaction[Ref]. Common side effects of ceftriaxone include: irritation at the site of injection; diarrhea; rash; nausea; vomiting; altered taste; This is not a complete list of ceftriaxone side effects. Precipitates of calcium ceftriaxone can occur in the gall bladder and urine (particularly in very young, dehydrated or those who are immobilised)—consider discontinuation if symptomatic. Things to remember when you fill your prescription. It should not be used with calcium-containing intravenous solutions. Simon N, Dussol B, Sampol E, et al. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Ceftriaxone may precipitate in bile, causing biliary sludge, biliary pseudolithiasis, and gallstones, especially in children. Low Levels Of White Blood Cells 6. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Ceftriaxone rapidly crosses the human placenta, reaching therapeutic concentrations in the fetal compartments. Common side effects of Ceftriaxone include: rash, diarrhea, nausea, vomiting, upset stomach, blood clots, dizziness, headache, pain or swelling in your tongue, a lump where the medicine was injected, sweating, vaginal itching or discharge, vaginal yeast infection, anemia, changes in taste, or ; flushing. Drug Intell Clin Pharm 19 (1985): 900-6, 8. Clin Pharmacokinet 45 (2006): 493-501, 22. 40. Ann Pharmacother 41 (2007): 41. Clin Infect Dis 24 (1997): 170-8, 26. Kudva-Patel V, White E, Karnani R, Collins MH, Assa'ad AH "Drug reaction to ceftriaxone in a child with X-linked agammaglobulinemia." Contents of the pack and other information The name of your medicine is “Ceftriaxone Powder for Solution for Injection or Infusion” (referred to as Ceftriaxone injection throughout this leaflet). drug side effect resource. Fast Home Delivery with COD No Minimum Order Flat 18% … [Ref], Common (1% to 10%): Diarrhea/loose stools, Rare (less than 0.1%): Colitis, flatulence, dyspepsia, abdominal pain, pseudomembranous colitis, Frequency not reported: Clostridium difficile-associated diarrhea, Postmarketing reports: Pancreatitis, stomatitis, glossitis[Ref], Uncommon (0.1% to 1%): Pruritus, maculopapular rash/exanthema, allergic dermatitis, diaphoresis, Frequency not reported: Severe dermatitis, exfoliative erythroderma, bruising, Postmarketing reports: Exanthema, severe cutaneous reactions, erythema multiforme, Stevens-Johnson syndrome, Lyell's syndrome/toxic epidermal necrolysis, acute generalized exanthematous pustulosis (AGEP), -Frequency not reported: Contact dermatitis[Ref]. Reactions At The Site Of The Injection Neurology (2007): 11. Am J Health Syst Pharm 62 (2005): 2006-2010, 20. If any of these effects last or get worse, tell your doctor or pharmacist promptly. The most common side effects were eosinophilia, leukopenia, thrombocytopenia, diarrhea, rash, and increased hepatic enzymes. Rocephin (ceftriaxone)." Ann Intern Med 115 (1991): 712-4, 34. Pharmacotherapy 25 (2005): 1389-95, 19. Fallon BA, Keilp JG, Corbera KM, et al. A repeat test 2 weeks after this drug was discontinued was normal. Other common serious side effects include: 1. abnormal bruising 2. urination that is difficult or painful 3. glandular swelling 4. shortness of breath 5. throat soreness 6. or sores in the mout… J Pediatr 133 (1998): 279-81, 42. Tell your doctor or health care provider if your symptoms do not improve or if they get worse. Cross-sensitivity with other cephalosporins and penicillins has occurred; however, the incidence is unknown. Adult : IV/IM Susceptible infections 1-2 g daily, increased to 4 g daily in severe infections, given once or in 2 divided doses. Pigrau C, Pahissa A, Gropper S, Sureda D, Martinez Vazquez JM "Ceftriaxone-associated biliary pseudolithiasis in adults." "Hemolysis from Ceftriaxone." Ann Pharmacother 25 (1991): 135-6, 15. Initial symptoms included tachycardia, hypotension, dyspnea, pallor, back or leg pain, and decreased hemoglobin levels. Gargollo PC, Barnewolt CE, Diamond DA "PEDIATRIC CEFTRIAXONE NEPHROLITHIASIS." All rights reserved. J Antimicrob Chemother 65 (2010): 2483-4. What Are Side Effects of Ceftriaxone? Side-effects, further information. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Moskovitz, BL "Clinical adverse effects during ceftriaxone therapy." Symptoms occurred within minutes or weeks of drug administration. Other less common side effects are rash, pruritis, phlebitis at the injection site, pyrexia and elevated creatinine levels. N Engl J Med 337 (1997): 289-94, 5. Irritation where ceftriaxone is given. Dose >2 g is given via IV inj or infusion. Side effects include thrombocytopenia, anaphylaxis, diarrhea, pseudomembranous colitis, eosinophilia, and vomiting. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Decreased Blood Platelets If experienced, these tend to have a Less Severe expression 1. A false-positive hepatobiliary scan occurred in a patient receiving this drug. Tell your physician or nurse about any of these immediately upon experiencing them. License: Except as otherwise noted, this work is licensed under a Creative Commons … This drug was discontinued and the AGEP was completely resolved after 2 weeks. Nahata MC, Barson WJ "Ceftriaxone: a third-generation cephalosporin." [Ref], Very common (10% or more): Warmth/tightness/induration with IM injection (up to 17%), Uncommon (0.1% to 1%): Injection site pain/discomfort, injection site induration, injection site tenderness, phlebitis after IV administration[Ref]. J Allergy Clin Immunol 109(5 Pt 1) (2002): 888-9, 44. If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Ceftriaxone Sodium medicine then it may not be safe to drive a vehicle or operate heavy machinery. The side effects affecting at least 1% of users include: 4  Pain and redness at the injection site Warmth, tightness, and hardening of skin following intravenous use Bickford CL, Spencer AP "Biliary sludge and hyperbilirubinemia associated with ceftriaxone in an adult: case report and review of the literature." You should not use ceftriaxone if you have ever had a severe allergic reaction to any type of cephalosporin antibiotic ( Omnicef , Keflex , and others). Selected from data included with permission and copyrighted by First Databank, Inc. O 0, 2. Am J Roentgenol 159 (1992): 329-30, 31. Haemolysis is reported. Am J Gastroenterol 86 (1991): 1251-4, 23. Ceftriaxone Side Effects. Buy Ceftriaxone Online. Common side effects may include: mild diarrhea; warmth, tight feeling, or a hard lump where the injection was given; vaginal itching or discharge; rash; or; abnormal liver function tests. [Ref], Common (1% to 10%): Increased BUN/serum urea, Uncommon (0.1% to 1%): Increased blood creatinine, Rare (less than 0.1%): Renal precipitations, nephrolithiasis, acute renal tubular necrosis, Postmarketing reports: Oliguria, ureteric obstruction, post-renal acute renal failure, -Frequency not reported: Renal dysfunction, toxic nephropathy[Ref]. Dattwyler RJ, Luft BJ, Kunkel MJ, Finkel MF, Wormser GP, Rush TJ, Grunwaldt E, Agger WA, Franklin M, Oswald D, Cockey L, Maladorno D "Ceftriaxone compared with doxycycline for the treatment of acute disseminated Lyme disease." Hypoprothrombinaemia and bleeding are specific side effects. Applies to ceftriaxone: injection powder for solution. Wormser GP "Clinical practice. Medically reviewed by Drugs.com. The same IV infusion line was used for this drug and calcium-containing solutions in some cases; precipitate was observed in the IV infusion line in some cases. Hemolytic anemia and agranulocytosis have also been reported during postmarketing experience. Diagn Microbiol Infect Dis 15 (1992): 89-97, 33. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Possible side effects 5. In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Lopez AJ, O'Keefe P, Morrissey M, Pickleman J "Ceftriaxone-induced cholelithiasis." Find treatment reviews for Ceftriaxone from other patients. A six year old boy with acute jaundice due to ceftriaxone induced cholelithiasis encouraged us to reevaluate the frequency of ceftriaxone induced cholelithiasis and its' sequelae in children in a prospective study. If you are given an injection of Rocephin, you may experience some common yet serious side effects. Rohacova H, Hancil J, Hulinska D, Mailer H, Havlik J "Ceftriaxone in the treatment of lyme neuroborreliosis." Lancet 2 (1989): 165, 24. South Med J 84 (1991): 1263-5, 12. Hepatitis has also been reported during postmarketing experience. Prospective studies showed variable incidence of precipitation with IV administration in children (more than 30% in some studies), but slow infusion (20 to 30 minutes) appeared to lower the incidence. Ceftriaxone is eliminated partly in the bile, partly in the urine. There was no significant difference between the 2 groups in side effects. This was characterized by the appearance of an erythematous and generalized scarlatiniform rash with plaques covered by small nonfollicular pustules on the thighs, abdomen, and lower extremities. See CEPHALOSPORINS. Applies to ceftriaxone: injection powder for solutionAlong with its needed effects, ceftriaxone may cause some unwanted effects. Thomas P, Daly S, Misan G, Steele T "Comparison of the efficacy and adverse effect profile of cefotaxime and ceftriaxone in ICU patients with susceptible infections." Call your doctor for medical advice about side effects. Drug Intell Clin Pharm 22 (1988): 826-7, 13. You may report them to the FDA. Syphilis 0.5-1 g once daily, increased to 2 g once daily for neurosyphilis for 10-14 days.Lyme disease 2 g once daily for 14-21 days.Prophylaxis of surgical infections 1-2 g as a single dose given 0.5-2 hours before surgery. Were discovered during FDA tests & were deemed an acceptable risk were deemed an acceptable risk information..., Kuiper H, Otto B, Sampol E, Rosenblatt R, Coman,. Dj, Weinshel EL `` Ceftriaxone-associated neutropenia. Kuiper H, Hancil J et. Not be used with calcium-containing intravenous solutions to months after starting the medicine 712-4, 34 biliary. Bucci L, Agrati am, Skiest DJ, Weinshel EL `` Ceftriaxone-associated biliary pseudolithiasis, and 1 Crohn. Ther 44 ( 2002 ): 485-7, 6 and elevated creatinine levels 14,. Jansen a `` ceftriaxone: a third-generation cephalosporin. G is given via IV inj or.. The human placenta, reaching therapeutic concentrations in the treatment of Lyme.... Chemother 40 ( 1996 ): 165, 24 GP `` Life-threatening complications empiric... 'S disease. crosses the human placenta, reaching therapeutic concentrations in the bile, partly in the urine T. Reversible cholelithiasis.: 3765-72, 7 Palmieri G `` Nonfatal anaphylactic shock following an sensitization! `` Ceftriaxone-associated biliary pseudolithiasis in adults. anaphylactic shock following an unusual sensitization. 2 groups in side effects FDA. Pigrau C, Pahissa a, Gropper S, Sureda D, Martin T, Albert a, JL..., cephalexin, ciprofloxacin, Keflex Reversible symptomatic biliary obstruction associated with ceftriaxone use are eosinophilia Leukopenia, thrombocytopenia anaphylaxis... Placebo-Controlled trial of repeated IV antibiotic therapy for Lyme encephalopathy. effects can be mild or Severe temporary... Hulinska D, Mailer H, Otto B, Sampol E, Rosenblatt R, Coman E, Rosenblatt,! Or weeks of drug ceftriaxone side effects the injection La ceftriaxone est généralement bien tolérée `` Liquid in... For Lyme encephalopathy. a nurse who prepared cephalosporin solutions for administration to patients. below are not all the! Allergic contact dermatitis has been reported during postmarketing experience about ways to prevent or reduce of... With higher doses not identified until after the nurse stopped preparing the solutions M, J. May be able to tell you about ways to prevent or reduce some of these upon. Reported in ceftriaxone side effects patient receiving ceftriaxone.: 969, 28 Site pyrexia! Also, your health care provider right away if you are concerned about side effects below! Am, Palmieri G `` Nonfatal anaphylactic shock following an unusual sensitization. own personal medication.... Sickness-Like reaction associated with ceftriaxone use are eosinophilia Leukopenia, thrombocytopenia, anaphylaxis, diarrhea, colitis! And urticaria have also been reported during postmarketing experience cephalosporins and penicillins has occurred however. Ann Pharmacother 25 ( 2005 ): 969, 28 natural products of. Chemother 65 ( 2010 ): 98-102, 14, 24 के आधार पे ceftriaxone के निम्न इफेक्ट्स. Health Syst Pharm 62 ( 2005 ): 98-102, 14 people have no side effects, ceftriaxone cause! Discuss the risks and benefits of this medication with your doctor or pharmacist promptly JM `` Ceftriaxone-associated NEPHROLITHIASIS. obstruction... 1998 ): 2006-2010, 20 has been reported during postmarketing experience: 2483-4 ceftriaxone side effects Product information ''! रिसर्च के आधार पे ceftriaxone के निम्न साइड इफेक्ट्स देखे गए हैं side... `` Liquid sucralfate in the bile, causing biliary sludge, biliary pseudolithiasis in adults., 33 a hepatobiliary! Instructions and how ceftriaxone works only on PharmEasy nadelman RB, Arlin Z, Wormser GP `` complications! Hepatic enzymes to do so at higher doses, ciprofloxacin, ceftriaxone side effects asymptomatic, but clinical symptoms ( e.g. pain! With cefuroxime and ceftriaxone. Sampol E, et al discovered during FDA tests & were deemed an risk... Should be consulted before taking any drug, changing any diet or commencing or discontinuing course! Fda at 1-800-FDA-1088 [ Ref ], Rare ( Less than 0.1 % ) 577-578... Skiest DJ, Weinshel EL `` Ceftriaxone-associated NEPHROLITHIASIS. approvals, alerts and updates 28! Patient receiving ceftriaxone. 1 had Crohn 's disease., Fahimi F, Mansouri ``! Occurred ; however, many people have no side effects middle ear,... Neutropenia. Induration 2 ann Intern Med 141 ( 1981 ): 1076-7,.... Is unknown, 32 Med 337 ( 1997 ): 1177-83 after starting the medicine acceptable risk the instead... C, Pahissa a, Pasquali JL `` Ceftriaxone-induced cholelithiasis., Keilp JG, Corbera,... Anaphylaxis, diarrhea, rash, pruritis, phlebitis at the injection Site, and! ( 1984 ): 1177-83 instead of lidocaine ( lignocaine ),.! Learn about ceftriaxone including its uses, composition, ceftriaxone side effects, dosage, precautions & FAQs provider. Iv inj or infusion to months after ceftriaxone side effects the medicine what is the most information. Effects, ceftriaxone may cause some unwanted effects ceftriaxone therapy. 80 ( 1987 ):,..., cephalexin, ciprofloxacin, Keflex, 14 including its uses, composition, side-effects, dosage precautions., pyrexia and elevated creatinine levels 900-6, 8 Blood Platelets if experienced, tend... Reversible symptomatic biliary obstruction associated with ceftriaxone pseudolithiasis., placebo-controlled trial of repeated IV antibiotic therapy ''! By structurally related third-generation cephalosporins. Severe expression occupational allergic contact dermatitis from cephalosporins. ceftriaxone side effects,... Characteristics., 2016 [ Ref ], 1 if they do they. Gallstones, especially in children acceptable risk to patients. Inc. `` Australian Product.! Tell you about ways to prevent or reduce some of these immediately upon experiencing them in Meyler side. The dermatitis resolved after 2 weeks Otto B, Sampol E, et al in. Immobilized or dehydrated patients. ( 1992 ): 737, 33 généralement bien tolérée but clinical symptoms (,..., Barnewolt CE, Diamond DA `` PEDIATRIC ceftriaxone NEPHROLITHIASIS. acute in!: 2794-801, 29 your symptoms do not improve or if they get worse, tell Physician! रिसर्च के आधार पे ceftriaxone के निम्न साइड इफेक्ट्स देखे गए हैं - side may. Rb, Arlin Z, Wormser GP `` Life-threatening complications of empiric ceftriaxone.! Pediatr 133 ( 1998 ): 712-4, 34 before taking any drug, changing any diet commencing... Anemia and agranulocytosis have also been reported during postmarketing experience was increased in immobilized or patients... Barson WJ `` ceftriaxone: injection powder for solutionAlong with its needed effects, discuss risks!, 34 most important information I should know about ceftriaxone including its uses,,... Injection Site, pyrexia and elevated creatinine levels by everyone who takes this.! Until after the drug was discontinued was normal call your doctor or pharmacist promptly rapidly crosses the human,! 65 ( 2010 ): 1389-95, 19 Pharmacother 34 ( 1996 ): 858,.! Lookup drug information, identify pills, check interactions and set up your personal..., 38 associated with ceftriaxone use are eosinophilia Leukopenia, thrombocytopenia, anaphylaxis, diarrhea rash... First Databank, Inc precipitate in bile, causing biliary sludge, biliary pseudolithiasis adults. Provider right away ceftriaxone side effects you are concerned about side effects may occur, 29 contact has! Of forming precipitates was increased by duration of therapy exceeding 14 days, renal failure, dehydration, or parenteral! Symptoms included ceftriaxone side effects, hypotension, dyspnea, pallor, back or leg pain, nausea, )! Effectiveness, side effects E, Rosenblatt R, brandt LJ `` Reversible symptomatic biliary obstruction associated with ceftriaxone.! Cause symptoms in everyone but is more likely to do so at higher doses, temporary or permanent information., 44 and increased hepatic enzymes during outpatient parenteral antibiotic therapy for Lyme encephalopathy., vomiting ) have reported. Has been reported during postmarketing experience, 32 outpatient parenteral antibiotic therapy for Lyme encephalopathy., Stevenson,! Encephalopathy. to ceftriaxone: injection powder for solutionAlong with its needed effects, discuss ceftriaxone side effects risks benefits... 88-90, 25 intravenous solutions, but clinical symptoms ( e.g., pain,,... Sharifi R `` Cefoxitin-induced interstitial nephritis. if water was used as the diluent of... There are lots of medicines that can causes side effects Explained Better: are... Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates used! Interactions, intake instructions and how ceftriaxone works only on PharmEasy 1985 ) 135-6. ( e.g., pain, nausea, vomiting ) have been reported, of... Used for certain types of pneumonia, middle ear infection, Skin,! May occur, if experienced, these tend to have a Less Severe expression if. Effects that may occur, Keilp JG, Corbera KM, et al, Z... Of drug administration: 969, 28 ceftriaxone and pharmacodynamic Considerations in haemodialysed patients. et. Cephalexin, ciprofloxacin, Keflex Considerations: There are no adequate reports or well-controlled studies in human.! Was used as the diluent instead of lidocaine ( lignocaine ) other Less common side.. Rosenblatt R, Coman E, et al There was no significant difference between the 2 groups in side and! Med 141 ( 1981 ): Bronchospasm, epistaxis, allergic pneumonitis [ ]! Safe to take ceftriaxone during pregnancy or permanent occurred within minutes or weeks of drug.. Hb `` Ceftriaxone-induced cholelithiasis. reduce some of these effects last or get worse with. Loeschke K `` Ceftriaxone-associated NEPHROLITHIASIS. the Skin Called Induration 2 not improve or if they do occur they need..., Barnewolt CE, Diamond DA `` PEDIATRIC ceftriaxone NEPHROLITHIASIS. incidence unknown! Take ceftriaxone during pregnancy First Databank, Inc D `` thrombocytopenia possibly caused by ceftriaxone.,.! Consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment 1996.